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A Master Conductor for Aggregate Clearance by Autophagy
Autophagic adapters including p62/SQSTM1 recognize polyubiquitinated autophagic targets such as toxic protein aggregates. Recently reporting in Molecular Cell, Filimonenko et al. provide evidence that the phosphatidylinositol 3-phosphate (PI3P) binding protein. Alfy interacts with p62, Atg5, and PI3...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974899/ https://ncbi.nlm.nih.gov/pubmed/20493804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.04.009 |
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