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Export of a hyperexpressed mammalian globular cytochrome b(5) precursor in Escherichia coli is dramatically affected by the nature of the amino acid flanking the secretory signal sequence cleavage bond

A chimeric mammalian globular cytochrome b(5) fused to Escherichia coli alkaline phosphatase signal sequence (SS) was used as a model probe to investigate the influence of substituting each one of the standard 20 amino acids at its N-terminus on the Sec-dependent export of the precursor to the perip...

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Detalhes bibliográficos
Principais autores: Kaderbhai, Naheed N, Ahmed, Khalil, Kaderbhai, Mustak A
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974826/
https://ncbi.nlm.nih.gov/pubmed/20506367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.411
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