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DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways

DNA double-strand breaks (DSBs) in eukaryotic cells can be repaired by non-homologous end-joining or homologous recombination. The complex containing the Mre11, Rad50 and Nbs1 proteins has been implicated in both DSB repair pathways, even though they are mechanistically different. To get a better un...

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Main Authors: de Jager, Martijn, Dronkert, Mies L. G., Modesti, Mauro, Beerens, Cecile E. M. T., Kanaar, Roland, van Gent, Dik C.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC29748/
https://ncbi.nlm.nih.gov/pubmed/11238998
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