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P2Y(13) receptor is responsible for ADP-mediated degranulation in RBL-2H3 rat mast cells

Extracellular ADP is known to play many important physiological roles. In this study, we identified the P2Y(13) receptor in a rat mast cell line (RBL-2H3) and explored the functional role of ADP, its endogenous agonist. ADP induced both intracellular calcium mobilization and release of hexosaminidas...

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Autores principales: Gao, Zhan-Guo, Ding, Yi, Jacobson, Kenneth A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974784/
https://ncbi.nlm.nih.gov/pubmed/20813187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2010.08.003
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