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Genetic control of the phenobarbital-induced shortening of plasma antipyrine half-lives in man

The mean half-life of antipyrine in the plasma of four sets of identical and four sets of fraternal twins after a single oral dose of 16 mg/kg of antipyrine was 12.7 ±(SD) 3.3 hr. After 2 wk on sodium phenobarbital (2 mg/kg daily) the half-life of antipyrine in the plasma of these twins was reduced...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Veseli, Elliot S., Page, John G.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1969
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297477/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5389794/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106186
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