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Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca(2+ )permeability and Mg(2+ )block

BACKGROUND: Members of the complex N-methyl-D-aspartate receptor (NMDAR) subfamily of ionotropic glutamate receptors (iGluRs) conventionally assemble from NR1 and NR2 subunits, the composition of which determines receptor properties. Hallmark features of conventional NMDARs include the requirement f...

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Detalhes bibliográficos
Main Authors: Cavara, Nora A, Orth, Angela, Hicking, Gordon, Seebohm, Guiscard, Hollmann, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974739/
https://ncbi.nlm.nih.gov/pubmed/20958962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-133
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