Decreased Toll-like receptor 8 expression and lower TNF-alpha synthesis in infants with acute RSV infection

BACKGROUND: Toll-like receptors (TLRs) are part of the innate immune system, able to recognize pathogen-associated molecular patterns and activate immune system upon pathogen challenge. Respiratory syncytial virus (RSV) is a RNA virus particularly detrimental in infancy. It could cause severe lower...

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Hauptverfasser: Bendelja, Kreso, Vojvoda, Valerija, Aberle, Neda, Cepin-Bogovic, Jasna, Gagro, Alenka, Mlinaric-Galinovic, Gordana, Rabatic, Sabina
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974671/
https://ncbi.nlm.nih.gov/pubmed/20946625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-143
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