Association of the CCR5 gene with juvenile idiopathic arthritis

The CC chemokine receptor 5 (CCR5) has been shown to be important in the recruitment of T-helper cells to the synovium, where they accumulate, drive the inflammatory process and the consequent synovitis and joint destruction. A 32 base-pair insertion/deletion variant (CCR5Δ32) within the gene leads...

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Autores principales: Hinks, A, Martin, P, Flynn, E, Eyre, S, Packham, J, Barton, A, Worthington, J, Thomson, W
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974598/
https://ncbi.nlm.nih.gov/pubmed/20463745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2010.25
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