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Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis

Interferon regulatory factor 4 (IRF-4) plays important functions in B- and T-cell development and immune response regulation and was originally identified as the product of a proto-oncogene involved in chromosomal translocations in multiple myeloma. Although IRF-4 is expressed in myeloid cells, its...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jo, Seung-Hee, Schatz, Jonathan H., Acquaviva, Jaime, Singh, Harinder, Ren, Ruibao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974585/
https://ncbi.nlm.nih.gov/pubmed/20585039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-234559
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