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Attenuation of Bacterial Virulence by Quorum Sensing-regulated Lysis

Genetically attenuated pathogenic bacteria have been extensively considered as vaccine candidates. However, insufficient attenuation has been a frequent limitation of this approach. Many pathogens use quorum sensing to escape host defense mechanism. Here, we hypothesized that quorum sensing can be m...

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Bibliographic Details
Main Authors: Silva, Anisia J., Benitez, Jorge A., Wu, Jian-He
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974442/
https://ncbi.nlm.nih.gov/pubmed/20673838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiotec.2010.07.025
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