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MbtH-Like Proteins as Integral Components of Bacterial Nonribosomal Peptide Synthetases(†)

The biosynthesis of many natural products of clinical interest involves large, multi-domain enzymes called nonribosomal peptide synthetases (NRPSs). In bacteria, many of the gene clusters coding for NRPSs also code for a member of the MbtH-like protein superfamily, which are small proteins of unknow...

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Detalhes bibliográficos
Main Authors: Felnagle, Elizabeth A., Barkei, John J., Park, Hyunjun, Podevels, Angela M., McMahon, Matthew D., Drott, Donald W., Thomas, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974439/
https://ncbi.nlm.nih.gov/pubmed/20845982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1012854
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