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Improved Fitting of Solution X-ray Scattering Data to Macromolecular Structures and Structural Ensembles by Explicit Water Modeling

[Image: see text] A new procedure, AXES, is introduced for fitting small-angle X-ray scattering (SAXS) data to macromolecular structures and ensembles of structures. By using explicit water models to account for the effect of solvent, and by restricting the adjustable fitting parameters to those tha...

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Main Authors: Grishaev, Alexander, Guo, Liang, Irving, Thomas, Bax, Ad
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2010
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974370/
https://ncbi.nlm.nih.gov/pubmed/20958032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja106173n
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