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Studies on collagenase from rheumatoid synovium in tissue culture

Fragments of synovium from patients with rheumatoid arthritis survive in defined tissue culture medium in the absence of added serum and, after 3-4 days, release into the medium enzyme capable of degrading undenatured collagen. Maximal activity is observed at pH 7-9 but the enzyme is inactive at pH...

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Detalhes bibliográficos
Main Authors: Evanson, John M., Jeffrey, John J., Krane, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1968
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC297435/
https://ncbi.nlm.nih.gov/pubmed/4302179
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