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Development of pH-sensitive Insulin Nanoparticles using Eudragit L100-55 and Chitosan with Different Molecular Weights

Insulin is a polypeptide hormone and usually administered for treatment of diabetic patients subcutaneously. The aim of this study was to investigate the efficiency of enteric nanoparticles for oral delivery of insulin. Nanoparticles were formed by complex coacervation method using chitosan of vario...

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Библиографические подробности
Главные авторы: Jelvehgari, Mitra, Zakeri-Milani, Parvin, Siahi-Shadbad, Mohammad Reza, Loveymi, Badir Delf, Nokhodchi, Ali, Azari, Zahra, Valizadeh, Hadi
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974163/
https://ncbi.nlm.nih.gov/pubmed/20686881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9488-7
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