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The Impact of Vehicles on the Mucoadhesive Properties of Orally Administrated Nanoparticles: a Case Study with Chitosan-4-Thiobutylamidine Conjugate

The aim of this study was to evaluate the impact of various vehicles on mucoadhesive properties of thiolated chitosan nanoparticles both in vitro and in vivo. Nanoparticles (NPs) were prepared by in situ gelation technique followed by labeling with fluorescein diacetate. Comparative studies on mucoa...

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Autors principals: Sakloetsakun, Duangkamon, Perera, Glen, Hombach, Juliane, Millotti, Gioconda, Bernkop-Schnürch, Andreas
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974160/
https://ncbi.nlm.nih.gov/pubmed/20668967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9479-8
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