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The Impact of Vehicles on the Mucoadhesive Properties of Orally Administrated Nanoparticles: a Case Study with Chitosan-4-Thiobutylamidine Conjugate

The aim of this study was to evaluate the impact of various vehicles on mucoadhesive properties of thiolated chitosan nanoparticles both in vitro and in vivo. Nanoparticles (NPs) were prepared by in situ gelation technique followed by labeling with fluorescein diacetate. Comparative studies on mucoa...

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Detalhes bibliográficos
Main Authors: Sakloetsakun, Duangkamon, Perera, Glen, Hombach, Juliane, Millotti, Gioconda, Bernkop-Schnürch, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974160/
https://ncbi.nlm.nih.gov/pubmed/20668967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9479-8
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