Formulation Development of Morphine Sulfate Sustained-Release Tablets and Its Bioequivalence Study in Healthy Thai Volunteers

The objectives of this study were to develop morphine sulfate sustained-release tablet formulations and to evaluate the bioequivalence compared with a commercial brand. The physicochemical properties of the formulated and commercial tablets were determined and compared. The bioequivalence investigat...

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Main Authors: Preechagoon, Detpon, Sumyai, Viroj, Chulavatnatol, Suvatna, Kulvanich, Poj, Tessiri, Thanee, Tontisirin, Khanittha, Pongjanyakul, Thaned, Uchaipichat, Verawan, Aumpon, Sirikul, Wongvipaporn, Chaiyasit
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974156/
https://ncbi.nlm.nih.gov/pubmed/20845089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9518-5
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