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Chitosan/Polyethylene Glycol Beads Crosslinked with Tripolyphosphate and Glutaraldehyde for Gastrointestinal Drug Delivery

This study reports on the preparation of chitosan (CS)/polyethylene glycol (PEG) hydrogel beads using sodium diclofenac (DFNa) as a model drug. Following the optimization of the polymer to drug ratio, the chitosan beads were modified by ionic crosslinking with sodium tripolyphosphate (TPP). The CS/P...

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Autors principals: Buranachai, Thawachinee, Praphairaksit, Nalena, Muangsin, Nongnuj
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974148/
https://ncbi.nlm.nih.gov/pubmed/20652459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9483-z
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