Safety, Immunogenicity and Duration of Protection of the RTS,S/AS02(D) Malaria Vaccine: One Year Follow-Up of a Randomized Controlled Phase I/IIb Trial

BACKGROUND: The RTS,S/AS02(D) vaccine has been shown to have a promising safety profile, to be immunogenic and to confer protection against malaria in children and infants. METHODS AND FINDINGS: We did a randomized, controlled, phase I/IIb trial of RTS,S/AS02(D) given at 10, 14 and 18 weeks of age s...

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Detalhes bibliográficos
Main Authors: Aide, Pedro, Aponte, John J., Renom, Montse, Nhampossa, Tacilta, Sacarlal, Jahit, Mandomando, Inacio, Bassat, Quique, Manaca, Maria Nélia, Leach, Amanda, Lievens, Marc, Vekemans, Johan, Dubois, Marie-Claude, Loucq, Christian, Ballou, W. Ripley, Cohen, Joe, Alonso, Pedro L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973956/
https://ncbi.nlm.nih.gov/pubmed/21079803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013838
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