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Identification of a helical intermediate in trifluoroethanol-induced alpha-synuclein aggregation
Because oligomers and aggregates of the protein α-synuclein (αS) are implicated in the initiation and progression of Parkinson’s disease, investigation of various αS aggregation pathways and intermediates aims to clarify the etiology of this common neurodegenerative disorder. Here, we report the for...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2973859/ https://ncbi.nlm.nih.gov/pubmed/20947801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012336107 |
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