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Human Cytomegalovirus Induces TGF-β1 Activation in Renal Tubular Epithelial Cells after Epithelial-to-Mesenchymal Transition

Human cytomegalovirus (HCMV) infection is associated epidemiologically with poor outcome of renal allografts due to mechanisms which remain largely undefined. Transforming growth factor-β1 (TGF-β1), a potent fibrogenic cytokine, is more abundant in rejecting renal allografts that are infected with e...

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Detalhes bibliográficos
Main Authors: Shimamura, Masako, Murphy-Ullrich, Joanne E., Britt, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973835/
https://ncbi.nlm.nih.gov/pubmed/21079788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001170
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