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Hormad1 Mutation Disrupts Synaptonemal Complex Formation, Recombination, and Chromosome Segregation in Mammalian Meiosis

Meiosis is unique to germ cells and essential for reproduction. During the first meiotic division, homologous chromosomes pair, recombine, and form chiasmata. The homologues connect via axial elements and numerous transverse filaments to form the synaptonemal complex. The synaptonemal complex is a c...

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Hlavní autoři: Shin, Yong-Hyun, Choi, Youngsok, Erdin, Serpil Uckac, Yatsenko, Svetlana A., Kloc, Malgorzata, Yang, Fang, Wang, P. Jeremy, Meistrich, Marvin L., Rajkovic, Aleksandar
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973818/
https://ncbi.nlm.nih.gov/pubmed/21079677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001190
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