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Variations in purine metabolism of cultured skin fibroblasts from patients with gout

Purine metabolism was studied in fibroblasts cultured from three patients with gout in an attempt to determine the biochemical bases of their disease. The rate of purine biosynthesis de novo was normal in one line of cells, but the rate of catabolism of adenine nucleotides to hypoxanthine and inosin...

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Bibliografski detalji
Glavni autori: Henderson, J. Frank, Rosenbloom, Frederick M., Kelley, William N., Seegmiller, J. Edwin
Format: Artigo
Jezik:Inglês
Izdano: 1968
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC297310/
https://ncbi.nlm.nih.gov/pubmed/5658584
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