Sites of action of sodium depletion on aldosterone biosynthesis in the dog

Secretion of cortisol, corticosterone, and aldosterone was measured in vivo in normal and sodium-depleted hypophysectomized dogs. Biogenesis of steroids was then measured in vitro with outer slices of the adrenals of the same dogs. In some studies, metyrapone or puromycin was added. In vivo, sodium...

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Pubblicato in:	J Clin Invest
Autori principali:	Davis, Warren W., Burwell, Lawrence R., Casper, Alfred G. T., Bartter, Frederic C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1968
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297298/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4297478/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105834
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