Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

Most antigenic peptides presented by MHC class I molecules result from the degradation of intracellular proteins by the proteasome. In lymphoid tissues and cells exposed to IFNγ, the standard proteasome is replaced by the immunoproteasome, in which all of the standard catalytic subunits β1, β2, and...

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Detalhes bibliográficos
Main Authors: Guillaume, Benoît, Chapiro, Jacques, Stroobant, Vincent, Colau, Didier, Van Holle, Benoît, Parvizi, Grégory, Bousquet-Dubouch, Marie-Pierre, Théate, Ivan, Parmentier, Nicolas, Van den Eynde, Benoît J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972972/
https://ncbi.nlm.nih.gov/pubmed/20937868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009778107
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