Suppression of glycine-(15)N incorporation into urinary uric acid by adenine-8-(13)C in normal and gouty subjects

Adenine inhibited the de novo synthesis of purines in both normal and gouty man as shown by inhibition of the incorporation of glycine-(15)N into urinary uric acid without altering the incorporation of glycine-(15)N into urinary creatinine. The diminished purine synthesis did not result in a diminut...

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Pubblicato in:	J Clin Invest
Autori principali:	Seegmiller, J. Edwin, Klinenberg, James R., Miller, John, Watts, R. W. E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1968
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5645862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105808
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