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Leukemogenesis: More Than Mutant Genes

Acute leukemias are characterized by recurring chromosomal aberrations and gene mutations which are critical to disease pathogenesis. It is now evident that epigenetic modifications including DNA methylation and histone modifications contribute significantly to the leukemogenic phenotype. An additio...

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Autors principals: Chen, Jianjun, Odenike, Olatoyosi, Rowley, Janet D.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972637/
https://ncbi.nlm.nih.gov/pubmed/20029422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2765
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