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Phosphate Regulates Embryonic Endochondral Bone Development

Phosphate is required for terminal differentiation of hypertrophic chondrocytes during postnatal growth plate maturation. In vitro models of chondrocyte differentiation demonstrate that 7mM phosphate, a concentration analogous to that of the late gestational fetus, activates the mitochondrial apopto...

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Autori principali: Zalutskaya, Alena A., Cox, Megan K., Demay, Marie B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972551/
https://ncbi.nlm.nih.gov/pubmed/19681042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22302
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