"Poker" association of weekly alternating 5-fluorouracil, irinotecan, bevacizumab and oxaliplatin (FIr-B/FOx) in first line treatment of metastatic colorectal cancer: a phase II study

BACKGROUND: This phase II study investigated efficacy and safety of weekly alternating Bevacizumab (BEV)/Irinotecan (CPT-11) or Oxaliplatin (OHP) associated to weekly 5-Fluorouracil (5-FU) in first line treatment of metastatic colorectal carcinoma (MCRC). METHODS: Simon two-step design: delta 20% (p...

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Main Authors: Bruera, Gemma, Santomaggio, Alessandra, Cannita, Katia, Baldi, Paola Lanfiuti, Tudini, Marianna, De Galitiis, Federica, Mancini, Maria, Marchetti, Paolo, Antonucci, Adelmo, Ficorella, Corrado, Ricevuto, Enrico
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972284/
https://ncbi.nlm.nih.gov/pubmed/20958992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-567
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