Hepatitis B virus core protein with hot-spot mutations inhibit MxA gene transcription but has no effect on inhibition of virus replication by interferon α

It has been reported that hepatitis B virus (HBV) core protein (HBc) can inhibit the transcription of human interferon-induced MxA gene. In this study, we investigated whether HBc protein mutations at hot spots (L60V, S87G and I97L) could still inhibit MxA transcription and the potential significanc...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhijian, Yu, Zhen, Huang, Fan, Zhang, Jin, Yang, Qiwen, Deng, Zhongming, Zeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972278/
https://ncbi.nlm.nih.gov/pubmed/20959021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-278
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