Mice Lacking Alkbh1 Display Sex-Ratio Distortion and Unilateral Eye Defects

BACKGROUND: Eschericia coli AlkB is a 2-oxoglutarate- and iron-dependent dioxygenase that reverses alkylated DNA damage by oxidative demethylation. Mouse AlkB homolog 1 (Alkbh1) is one of eight members of the newly discovered family of mammalian dioxygenases. METHODS AND FINDINGS: In the present stu...

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Hauptverfasser: Nordstrand, Line M., Svärd, Jessica, Larsen, Elisabeth, Nilsen, Anja, Ougland, Rune, Furu, Kari, Lien, Guro F., Rognes, Torbjørn, Namekawa, Satoshi H., Lee, Jeannie T., Klungland, Arne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972218/
https://ncbi.nlm.nih.gov/pubmed/21072209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013827
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