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TRANSCRIPTIONAL ACTIVATION OF THE SUPPRESSOR OF CYTOKINE SIGNALING–3 (SOCS3) GENE VIA STAT3 IS INCREASED IN F9 REX1 (ZFP-42) KNOCKOUT TERATOCARCINOMA STEM CELLS RELATIVE TO WILD TYPE CELLS

Rex1 (Zfp42), first identified as a gene that is transcriptionally repressed by retinoic acid (RA), encodes a zinc finger transcription factor expressed at high levels in F9 teratocarcinoma stem cells, embryonic stem (ES) cells, and other stem cells. Loss of both alleles of Rex1 by homologous recomb...

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Bibliographic Details
Main Authors: Xu, Juliana, Sylvester, Renia, Tighe, Ann P., Chen, Siming, Gudas, Lorraine J.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972193/
https://ncbi.nlm.nih.gov/pubmed/18237746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.038
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