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(S)-6-Chloro-4-cyclo­propyl­ethynyl-4-trifluoro­methyl-1H-3,1-benzoxazin-2(4H)-one

Two independent mol­ecules comprise the crystallographic asymmetric unit in the title anti­retroviral agent Efavirenz, C(14)H(9)ClF(3)NO(2), and these have noteworthy differences in conformation. The major difference relates to the orientation of the 2-cyclo­propyl­ethynyl residue relative to the si...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cuffini, Silvia, Howie, R. Alan, Tiekink, Edward R. T., Wardell, James L., Wardell, Solange M. S. V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2971961/
https://ncbi.nlm.nih.gov/pubmed/21578886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1600536809049101
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