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MEDELLER: homology-based coordinate generation for membrane proteins

Motivation: Membrane proteins (MPs) are important drug targets but knowledge of their exact structure is limited to relatively few examples. Existing homology-based structure prediction methods are designed for globular, water-soluble proteins. However, we are now beginning to have enough MP structu...

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Autori principali: Kelm, Sebastian, Shi, Jiye, Deane, Charlotte M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2971581/
https://ncbi.nlm.nih.gov/pubmed/20926421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq554
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