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Characterizing molecular adaptation: a hierarchical approach to assess the selective influence of amino acid properties

Motivation: A number of methods for detecting positive selection in protein coding DNA sequences are based on whether each site/region has a non-synonymous to synonymous substitution rates ratio ω greater than one. However, a site/region may show a relatively large number of non-synonymous mutations...

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Bibliografiska uppgifter
Huvudupphovsmän: Datta, Saheli, Prado, Raquel, Rodríguez, Abel, Escalante, Ananías A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2971574/
https://ncbi.nlm.nih.gov/pubmed/20847216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq532
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