The Angiotensin-Converting Enzyme 2/Angiogenesis-(1–7)/Mas Axis Confers Cardiopulmonary Protection against Lung Fibrosis and Pulmonary Hypertension

Rationale: An activated vasoconstrictive, proliferative, and fibrotic axis of the renin angiotensin system (angiotensin-converting enzyme [ACE]/angiotensin [Ang]II/AngII type 1 receptor) has been implicated in the pathophysiology of pulmonary fibrosis (PF) and pulmonary hypertension (PH). The recent...

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Autori principali: Shenoy, Vinayak, Ferreira, Anderson J., Qi, Yanfei, Fraga-Silva, Rodrigo A., Díez-Freire, Carlos, Dooies, Autumn, Jun, Joo Yun, Sriramula, Srinivas, Mariappan, Nithya, Pourang, Dorna, Venugopal, Changaram S., Francis, Joseph, Reudelhuber, Timothy, Santos, Robson A., Patel, Jawaharlal M., Raizada, Mohan K., Katovich, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2010
Soggetti:
D. Pulmonary Vascular Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970847/
https://ncbi.nlm.nih.gov/pubmed/20581171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200912-1840OC
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