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Transcriptional activation by pRB, and its coordination with SWI/SNF recruitment

A central question in cancer biology is why most tumor susceptibility genes are linked with only limited types of cancer. Human germ-line mutation of the retinoblastoma susceptibility gene Rb1 is closely linked with just retinoblastoma and osteosarcoma, although the gene is universally expressed. Fu...

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Autori principali: Flowers, Stephen, Beck, George R., Moran, Elizabeth
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970714/
https://ncbi.nlm.nih.gov/pubmed/20851996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2205
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