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Over expression of miR-100 is responsible for the low expression of ATM in the human glioma cell line: M059J
M059J and M059K cells were isolated from different portions of the same human malignant glioma. M059J cells are more radiosensitive than M059K cells due to the absence of DNA-PKcs and low-expression of ATM. The mechanism concerning the absence of DNA-PKcs in M059J is due to the frameshift mutation i...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2010
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970684/ https://ncbi.nlm.nih.gov/pubmed/20869334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.08.007 |
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