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Over expression of miR-100 is responsible for the low expression of ATM in the human glioma cell line: M059J

M059J and M059K cells were isolated from different portions of the same human malignant glioma. M059J cells are more radiosensitive than M059K cells due to the absence of DNA-PKcs and low-expression of ATM. The mechanism concerning the absence of DNA-PKcs in M059J is due to the frameshift mutation i...

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Bibliographic Details
Main Authors: Ng, Wooi Loon, Yan, Dan, Zhang, Xiangming, Mo, Yin-Yuan, Wang, Ya
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970684/
https://ncbi.nlm.nih.gov/pubmed/20869334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.08.007
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