Targeting DNA-PKcs and ATM with miR-101 Sensitizes Tumors to Radiation

BACKGROUND: Radiotherapy kills tumor-cells by inducing DNA double strand breaks (DSBs). However, the efficient repair of tumors frequently prevents successful treatment. Therefore, identifying new practical sensitizers is an essential step towards successful radiotherapy. In this study, we tested th...

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Bibliografiske detaljer
Main Authors: Yan, Dan, Ng, Wooi Loon, Zhang, Xiangming, Wang, Ping, Zhang, Zhaobin, Mo, Yin-Yuan, Mao, Hui, Hao, Chunhai, Olson, Jeffrey J., Curran, Walter J., Wang, Ya
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895662/
https://ncbi.nlm.nih.gov/pubmed/20617180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011397
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