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Methylation patterns in cell-free plasma DNA reflect removal of the primary tumor and drug treatment of breast cancer patients

Abnormal DNA methylation is a feature of most types of cancer, which is reflected in cell-free circulating DNA in plasma. It is, however, unknown whether surgical removal of the tumor and subsequent therapy induces changes in plasma DNA methylation, which can be used to monitor treatment. In this pi...

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Detalhes bibliográficos
Main Authors: Liggett, Thomas E., Melnikov, Anatoliy A., Marks, Jeffrey R., Levenson, Victor V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970661/
https://ncbi.nlm.nih.gov/pubmed/20473856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25363
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