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Genes Encoding Catalytic Subunits of Protein Kinase A and Risk of Spina Bifida
BACKGROUND: PRKACA and PRKACB are genes encoding the cAMP-dependent protein kinase A (PKA) catalytic subunits alpha and beta, respectively. PKA is known to be involved in embryonic development, as it downregulates the Hedgehog (Hh) signaling pathway, which is critical to normal pattern formation and...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970525/ https://ncbi.nlm.nih.gov/pubmed/16080189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20175 |
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