Interstitial collagenase (matrix metalloproteinase-1) expresses serpinase activity.

Human endothelial cells treated with either interleukin-1 beta, tumor necrosis factor-alpha, or phorbol myristate acetate secreted a metalloproteinase that hydrolyzed and inactivated the two major serine proteinase inhibitors (Serpins) found in plasma, alpha 1-proteinase inhibitor and alpha 1-antich...

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Pubblicato in:	J Clin Invest
Autori principali:	Desrochers, P E, Jeffrey, J J, Weiss, S J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296988/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1645757/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115262
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