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In vivo stimulation of the insulin receptor kinase in human skeletal muscle. Correlation with insulin-stimulated glucose disposal during euglycemic clamp studies.

To assess the relationship between insulin receptor (IR) kinase activity and insulin action in vivo in humans, we measured glucose disposal rates (GDR) during a series of euglycemic clamp studies. Simultaneously, we measured IR kinase activity in IRs extracted from skeletal muscle obtained by needle...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Freidenberg, G R, Suter, S L, Henry, R R, Reichart, D, Olefsky, J M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1991
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1645756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115257
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