Platelets of the Wistar Furth rat have reduced levels of alpha-granule proteins. An animal model resembling gray platelet syndrome.

Rats of the Wistar Furth (WF) strain have hereditary macrothrombocytopenia (large mean platelet volume [MPV] with increased platelet size heterogeneity and reduced platelet count). Ultrastructural studies suggest that this anomaly results from erratic subdivision of megakaryocyte cytoplasm into plat...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Jackson, C W, Hutson, N K, Steward, S A, Saito, N, Cramer, E M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2040691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115226
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