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Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptors.
Thyroid hormone (T3) resistance is inherited in most cases in an autosomal dominant manner. The disorder is characterized by elevated free thyroid hormone levels and partial resistance to thyroid hormone at the cellular level. Distinct single amino acid substitutions in the ligand binding domain of...
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| Yayımlandı: | J Clin Invest |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
1991
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296951/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2040690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115225 |
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