Thyroid hormone resistance syndrome. Inhibition of normal receptor function by mutant thyroid hormone receptors.

Thyroid hormone (T3) resistance is inherited in most cases in an autosomal dominant manner. The disorder is characterized by elevated free thyroid hormone levels and partial resistance to thyroid hormone at the cellular level. Distinct single amino acid substitutions in the ligand binding domain of...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Chatterjee, V K, Nagaya, T, Madison, L D, Datta, S, Rentoumis, A, Jameson, J L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1991
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296951/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2040690/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115225
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