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Ibuprofen prevents oxidant lung injury and in vitro lipid peroxidation by chelating iron.
Because ibuprofen protects from septic lung injury, we studied the effect of ibuprofen in oxidant lung injury from phosgene. Lungs from rabbits exposed to 2,000 ppm-min phosgene were perfused with Krebs-Henseleit buffer at 50 ml/min for 60 min. Phosgene caused no increase in lung generation of cyclo...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2173723/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114876 |
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