Immunogenicity in animals of a polysaccharide-protein conjugate vaccine against type III group B Streptococcus.

The native capsular polysaccharide of type III group B Streptococcus elicits a specific antibody response in only 60% of nonimmune human subjects. To enhance the immunogenicity of this polysaccharide, we coupled the type III polysaccharide to tetanus toxoid. Prior to coupling, aldehyde groups were i...

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Publié dans:	J Clin Invest
Auteurs principaux:	Wessels, M R, Paoletti, L C, Kasper, D L, DiFabio, J L, Michon, F, Holme, K, Jennings, H J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2243123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114858
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