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Change you can B(cell)eive in: recent progress confirms a critical role for B cells in type 1 diabetes

PURPOSE OF REVIEW: Here we review extant recent findings regarding the multiple roles of B cells in type 1 diabetes (T1D) and discuss how autoreactive B cells may become activated by a breach in B cell tolerance, and thereby initiate disease. Finally, we discuss the use of B cell-targeted therapies...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: O’Neill, Shannon K., Liu, Edwin, Cambier, John C.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2968699/
https://ncbi.nlm.nih.gov/pubmed/19502979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MED.0b013e32832e06a7
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