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Regulation of parathyroid hormone gene expression by hypocalcemia, hypercalcemia, and vitamin D in the rat.

In vivo in the rat 1,25(OH)2D3 decreases and a low calcium increases PTH mRNA levels. We now report the effect of 3 and 8 wk of changes in dietary vitamin D and calcium on PTH mRNA levels. PTH mRNA levels were increased by 3 wk of calcium deficiency (five times), a vitamin D-deficient diet (two time...

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Опубликовано в: :J Clin Invest
Главные авторы: Naveh-Many, T, Silver, J
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1990
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296864/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2212016/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114840
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