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The immunoglobulin G subclass composition of immune complexes in cystic fibrosis. Implications for the pathogenesis of the Pseudomonas lung lesion.

It has been shown that pulmonary macrophage (PM) phagocytosis of Pseudomonas aeruginosa (PA) is inhibited in the presence of serum from cystic fibrosis (CF) patients colonized by Pseudomonas, and that these sera contain high concentrations of IgG2 antibodies. The goal of these studies was to investi...

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Pubblicato in:J Clin Invest
Autori principali: Hornick, D B, Fick, R B
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2120286/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114836
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