Expression of ras oncogenes in cultured human cells alters the transcriptional and posttranscriptional regulation of cytokine genes.

Autonomous production of cytokines such as the hematopoietic colony-stimulating factors (CSFs), IL-1, or IL-6 has been demonstrated in numerous human and murine neoplasms, and may be involved in the pathogenesis of several paraneoplastic syndromes such as leukocytosis, fever, and hypercalcemia. Beca...

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Опубликовано в: :J Clin Invest
Главные авторы: Demetri, G D, Ernst, T J, Pratt, E S, Zenzie, B W, Rheinwald, J G, Griffin, J D
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1990
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296857/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2212010/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114833
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